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Natural esophageal defenses: Strengths and limitations

When certain natural mechanisms fail to adequately protect the mucosa, the esophagus is more susceptible to potentially harmful, acid-activated pepsin.

How esophageal defenses help — and how they can fall short

Acid + Pepsin = Painful Esophageal Symptoms

Experimental studies suggest that at a pH of 1.3 or above, acid alone will not injure the esophagus. However, the harmful effects of pepsin on the esophageal mucosa are maximal at pH 1-3.3. Raising the pH in the esophagus can decrease the activity of pepsin.1

Supplement your treatment program with Mylanta for symptom relief

  • Immediately neutralizes the residual acid from gastric refluxate
  • Provides symptomatic relief of hyperacidity associated with peptic esophagitis, peptic ulcer, gastritis, gastric hyperacidity, and hiatal hernia
  • Delivers powerful acid-fighting ingredients and contains simethicone to relieve symptoms of excess gas

Recommend liquid Mylanta for its strong acid-neutralizing power

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  1. Hirschowitz BI. Pepsin and the esophagus. Yale J Bio Med. 1999;72:133-143.
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